Artificial Intelligence
Pharmaceutical Industry

What a May 2025 JAMA Study Reveals About How Physicians Want AI to Work

By Noah Pines

As the life sciences industry accelerates its investment in AI-driven customer engagement, it’s critical to understand how physicians themselves are experiencing AI inside their workflow. A May 2025 JAMA Network Open study from Sutter Health -- widely referenced in professional society discussions, including recent AMA commentary -- offers one of the clearest real-world demonstrations of what “responsible, effective” AI adoption looks like in clinical practice.

For pharma commercial, insights and analytics professionals, this study is more than an operational case study: it signals a shift in physician expectations around what AI should accomplish, how seamlessly it should integrate, and what “value” looks like at the point of care. For those who are interested in reviewing the article, here is the link: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2833433

Ambient AI Shows Meaningful Reductions in Burnout and Cognitive Load

Sutter Health piloted an ambient AI documentation tool with 100 clinicians across eight medical groups, spanning primary care and specialty practices. The core question was simple: Could AI reduce the administrative burden that fuels burnout, without disrupting clinical flow?

The results were remarkable. The percentage of physicians spending an hour or less per week on after-hours notes climbed from 14% to 54%. The share who felt able to give patients their full attention rose from 58% to 93%, suggesting that the AI tool helped shift attention back to the human interaction rather than the laptop. Burnout indicators dropped from 42% to 35%, and validated measures of cognitive load -- including mental demand, rushed note completion, and task difficulty -- all showed statistically significant improvement.

These are not incremental gains; they reflect a structural reduction in “desktop medicine,” one of the leading drivers of physician dissatisfaction.

Workflow Fit and HCP Pull Are the New Success Criteria for AI

Importantly, the study also highlights that early limitations -- lack of full EHR integration, limited customization, specialty-specific gaps -- could have derailed adoption. But once integration improved, Sutter moved to an opt-in model, and physicians pulled the technology into their workflow rather than resisting it. Simple onboarding, self-service enrollment, and clinical champions helped accelerate scaling. By late 2025, more than 1.2 million notes had been generated through ambient AI, growing by 50,000 per week.

For biopharma, some implications include:

  • Physicians embrace AI that gives time back -- not AI that adds steps.
  • Workflow-native design and seamless integration matter more than algorithmic sophistication.
  • Positive clinical AI experiences will shape receptivity to AI-powered engagement, content, and insights from industry partners.

As pharma deploys AI tools across medical, commercial, and field organizations, aligning with this physician-centered model of “ambient, unobtrusive, workflow-aligned AI” will be essential for credibility and adoption.